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- Title
Hypersensitivity pneumonitis caused by Fusarium napiforme in a home environment.
- Authors
Lee, S-K.; Kim, S-S.; Nahm, D-H.; Park, H-S.; Oh, Y-J.; Park, K-J.; Kim, S-O.; Kim, S-J.
- Abstract
Background: We report a case of hypersensitivity pneumonitis (HP) in a 17-year-old male student caused by Fusarium napiforme found in his home environment. Methods: The patient was diagnosed according to history, chest radiograph, spirometry, high-resolution chest CT, and transbronchial lung biopsy. To identify the causative agent, cultured aeromolds were collected by the open-plate method. From the main fungi cultured, fungal antigens were prepared, and immunoblot analysis with the patient's serum and each fungal antigen was performed. Results: Five fungal species were isolated from the patient's home. Immunoblotting analysis with the patient's serum demonstrated more than 10 IgG-binding fractions to F. napiforme extract only, while little binding was noted with the other fungal antigens. Conclusions: We should be aware that HP may be caused by F. napiforme in the home environment.
- Subjects
HYPERSENSITIVITY pneumonitis; FUSARIUM; DIAGNOSTIC immunoblotting; ETIOLOGY of diseases; PHYSIOLOGY
- Publication
Allergy, 2000, Vol 55, Issue 12, p1190
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1034/j.1398-9995.2000.00650.x