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- Title
Natural, Designed and Engineered Metalloenzymes: Structure, Catalytic Mechanisms and Applications.
- Authors
Leone, Linda; Nastri, Flavia; Lombardi, Angela
- Abstract
Lin and coworkers designed a four-residue mutant of Mb to introduce the key structural features found in peroxidase-active sites, turning the O SB 2 sb -carrier protein into an efficient artificial peroxidase. Bioinorganic chemists have become engaged in the challenge of elucidating the molecular mechanisms that govern how protein scaffolds modulate the properties of metal cofactors.
- Subjects
ENGINEERING design; SYNTHETIC proteins; HEMOPROTEINS; STRUCTURAL engineering; SCAFFOLD proteins
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 18, p14255
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms241814255