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- Title
Oxidative stress in atherosclerosis-prone mouse is due to low antioxidant capacity of mitochondria.
- Authors
Oliveira, Helena C. F.; Cosso, Ricardo G.; Alberici, Luciane C.; Maciel, Evelise N.; Salerno, Alessandro G.; Dorighello, Gabriel G.; Velho, Jesus A.; De Faria, Eliana C.; Vercesi, Aníbal E.
- Abstract
Presents a study which examined the mitochondrial function and production of reactive oxygen species in the atherosclerosis-susceptible, hypercholesterolemic low density lipoprotein (LDL) receptor knockout mice. Results of the isolation of mitochondria from the LDL mice; Oxidizing of pyridine nucleotides in LDL receptor knockout mouse; Secretion and synthesis of triglycerides and cholesterol in the livers of hypercholesterolemic low density lipoprotein (LDL) receptor knockout mice.
- Subjects
MITOCHONDRIA; REACTIVE oxygen species; ATHEROSCLEROSIS; LOW density lipoproteins; LABORATORY mice; PYRIDINE nucleotides; TRIGLYCERIDES; CHOLESTEROL
- Publication
FASEB Journal, 2005, Vol 19, Issue 2, p278
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.04-2095fje