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- Title
Ipsi- and Contralateral Moxibustion Generate Similar Analgesic Effect on Inflammatory Pain.
- Authors
Zuo, Chuan-Yi; Lv, Peng; Zhang, Cheng-Shun; Lei, Ru-Xue; Zhou, Wei; Wu, Qiao-Feng; Luo, Ling; Tang, Yong; Yin, Hai-Yan; Yu, Shu-Guang
- Abstract
The aim of this study was to investigate whether contralateral moxibustion would generate a similar analgesic effect with ipsilateral moxibustion. Contra- and ipsilateral moxibustion were separately applied to Zusanli (ST36) acupoints of inflammatory pain mice. The analgesic effect was evaluated, respectively, by licking/biting time (LBT) of formalin-induced inflammatory pain and thermal withdrawal latency (TWL) of complete Freund's adjuvant- (CFA-) induced inflammatory pain. For formalin-induced pain, compared with formalin group, the total LBT of ipsi- and contralateral moxibustion reduced in both phase I and phase II, but there was no significant difference between ipsi- and contralateral moxibustion. For CFA-induced inflammatory pain, compared with CFA group, TWL of ipsi- and contra-Moxi groups increased immediately after moxibustion intervention; however there was no obvious difference between ipsi- and contralateral moxibustion at any timepoint. It indicated that contralateral moxibustion had a similar analgesic effect with ipsilateral moxibustion in both formalin- and CFA-induced pain. These results suggest that both ipsi- and contralateral moxibustion could be applied for pain relief.
- Subjects
INFLAMMATION treatment; PAIN management; ACUPUNCTURE points; ANALGESIA; ANIMAL experimentation; MICE; MOXIBUSTION; TREATMENT effectiveness
- Publication
Evidence-based Complementary & Alternative Medicine (eCAM), 2019, p1
- ISSN
1741-427X
- Publication type
Article
- DOI
10.1155/2019/1807287