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- Title
Emergence of Pathogenicity in Lagoviruses: Evolution from Pre-existing Nonpathogenic Strains or through a Species Jump?
- Authors
Esteves, Pedro José; Abrantes, Joana; Bertagnoli, Stéphane; Cavadini, Patrizia; Gavier-Widén, Dolores; Guitton, Jean-Sébastien; Lavazza, Antonio; Lemaitre, Evelyne; Letty, Jérôme; Lopes, Ana Margarida; Neimanis, Aleksija S.; Ruvoën-Clouet, Nathalie; Le Pendu, Jacques; Marchandeau, Stéphane; Le Gall-Reculé, Ghislaine
- Abstract
The article deals with mechanism of genetic determinism of pathogenecity in Rabbit hemorrhagic disease virus (RHDV) and European brown hare syndrome virus (EBHSV). Topics discussed include the types of RHDV strains, the evolution of the viruses from pre-existing nonpathogenic viruses and species jump, and documentation of RHDV strains in Iberian hares. The origins of European leporids with lagoviruses are also discussed.
- Subjects
RABBIT calicivirus; RABBIT calicivirus disease; RABBIT diseases; LEPORIDAE; GENETICS of virus diseases; DIAGNOSIS
- Publication
PLoS Pathogens, 2015, Vol 11, Issue 11, p1
- ISSN
1553-7366
- Publication type
Opinion
- DOI
10.1371/journal.ppat.1005087