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- Title
Benzocoumarin as a potential scaffold: A review of its biomedical activities.
- Authors
Jasim, Sara Firas; Waheed, Sarah Ahmed; Jebir, Rahma Mowaffaq; Ismael, Reem Nadher; Mustafa, Yasser Fakri
- Abstract
Coumarin derivatives have piqued the curiosity of many researchers in the medicine and industry fields due primarily to their chemical diversity and bioactivities. Amongst coumarin derivatives, benzocomarins have garnered significant interest from pharmaceutical chemists in the past few years. Many scientific studies in the literature reported the bioactivities of natural and synthesized benzocoumarin derivatives. The focus of this review was on the general synthetic routes of benzocoumarins, besides the depiction of their biological activities, particularly those pertaining to anticancer, antioxidant, antibacterial, antiviral, and antidiabetic potentials. The authors concluded that the benzocoumarin backbone is an attractive scaffold that sheds light on exploring new drug candidates with novel or improved bioactivities.
- Subjects
COUMARINS; COUMARIN derivatives; SCIENTIFIC literature; HYPOGLYCEMIC agents; SPINE; CHEMISTS
- Publication
Archivos Venezolanos de Farmacología y Terapéutica, 2022, Vol 41, Issue 2, p139
- ISSN
0798-0264
- Publication type
Article
- DOI
10.5281/zenodo.6578848