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- Title
Kinetic Modeling of Ethanol Production by Scheffersomyces stipitis from Xylose.
- Authors
Farias, Daniele; Andrade, Rafael; Maugeri-Filho, Francisco
- Abstract
This work focuses on the kinetics of ethanol production by Scheffersomyces stipitis on xylose with the development of a mathematical model considering the effect of substrate and product concentrations on growth rate. Experiments were carried out in batch and continuous modes, with substrate concentration varying from 7.2 to 145 g L. Inhibitory effects on cell growth, substrate uptake, and ethanol production rates were found to be considerable. Kinetic parameters were obtained through linear and non-linear regression methods. Experiments in continuous mode were performed at different dilution rates to evaluate the inhibitory effect of ethanol. A mixed mathematical model which combined Andrews and Levenspiel's models, combining substrate and product inhibition, was used. A quasi-Newton routine was applied to obtain a more accurate fitting of kinetic parameters. The parameters such as cell to product factor ( Y) and limiting cell yield ( Y) were shown to be dependent on substrate concentration. The kinetic model fitted satisfactorily the experimental data.
- Subjects
ETHANOL as fuel; BIOMASS production; XYLOSE; MATHEMATICAL models; NONLINEAR regression; YEAST
- Publication
Applied Biochemistry & Biotechnology, 2014, Vol 172, Issue 1, p361
- ISSN
0273-2289
- Publication type
Article
- DOI
10.1007/s12010-013-0546-y