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- Title
Marriage and child bearing in patients with transfusion-dependent thalassemia major.
- Authors
Zafari, Mandana; Kosaryan, Mehrnoush
- Abstract
Aim With good care, patients with transfusion-dependent thalassemia major ( TDTM) can reach older ages, marry and reproduce. This study was conducted by the Thalassemia Research Center. Material and Methods Medical notes of all TDTM patients and all non-transfusion-dependent thalassemia major ( NTDTM) patients were reviewed from July to December 2012. Also, patients were interviewed. The questionnaire was made in consultation with research methodology experts and reliability was achieved by a pilot study of 12 patients, by the test-retest method (r = 0.9). Epidemiologic characteristics of patients and the pregnancy outcomes were recorded. Descriptive statistics were used with spss 17. Results Four hundred and nineteen medical records were reviewed. Three hundred and forty-five (82.5%) were TDTM. One hundred and seventy-five (50.7%) were female with a mean age of 25.4 ± 7.05 years and 42 (25%) had been married. Mean age of menarche and marriage was 15.4 ± 1.6 and 21.8 ± 4.5 years, respectively. Total number of live children is nine so far. Mode of delivery in female patients was cesarean section. Almost 78% of newborns weighed 2500-4000 g. Almost 22% of pregnancies were assisted. Male patients consisted of 170 (49.3%) and 55 (32.3%) of them had been married. Mean age at marriage was 24.27 ± 3.5 years. Conclusions With better management, patients with TDTM can reach the age of reproduction. Medical teams should be prepared for this possibility.
- Subjects
IRAN; CONFIDENCE intervals; FERTILITY; INTERVIEWING; MARRIAGE; EVALUATION of medical care; PREGNANCY; QUESTIONNAIRES; RESEARCH funding; DATA analysis software; BETA-Thalassemia; DESCRIPTIVE statistics; DELAYED puberty; DISEASE complications
- Publication
Journal of Obstetrics & Gynaecology Research, 2014, Vol 40, Issue 8, p1978
- ISSN
1341-8076
- Publication type
Article
- DOI
10.1111/jog.12427