We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
EPIDEMIOLOGICAL, CLINICAL AND PROGRESSIVE SPECTRUM OF MEASLES CASES ADMITTED TO „DR. VICTOR BABES“ CLINICAL HOSPITAL FOR INFECTIOUS AND TROPICAL DISEASES, BUCHAREST DURING THE ACTUAL OUTBREAK.
- Authors
Vancea, Geta; Stoenescu, Andreea; Ianache, Irina; Iordache, Cristina; Ungureanu, Eugenia; Apostol, Carmen; Enache, Gh.; Ispas, Dana; Voicu-Parvu, Nicoleta; Serban, D.; Cebuc, Roxana; Malciolu-Nica, Alexandra; Dascalu, Ana-Maria; Ceausu, Emanoil; Calistru, Petre
- Abstract
Introduction. Starting with 2016 Romania had to face an alarming measles outbreak due to the continuous poor vaccination coverage. The outbreak associated an increased number of complications and deaths. Materials and methods. We performed a retrospective study, on a group of patients with measles, admitted to „Dr. Victor Babes“ Hospital. Epidemiological data, clinical characteristics and the results of the biological samples were obtained from the patient's medical records between January 2016 and December 2017. Results. Out of the 632 patients, 341 (53.9%) were males. Most of them (39.2%) were children, between 1 and 4 year-old, while 19.6% were infants. A quarter of the patients (31.3%) had familial contact with a measles case. The vaccination history was unknown in 44.3% cases; almost half of the patients (47.1%) were unvaccinated. Almost all of them developed viral complications, 84.1% being diagnosed with interstitial pneumonia. Bacterial pneumonia was diagnosed in 15.0% cases, out of which 45.2% were also associated with respiratory failure. Six patients required transfer to the pediatric intensive care unit for respiratory support and 2 died. Other complications were: laryngitis 8.2%, otitis 12.0% of the cases. Also 61.77% of the patients were diagnosed with enterocolitis. There was no case complicated with encephalitis. 101 (15.9%) patients developed liver cytolysis, while dyselectrolytemia was present in 94 (14.8%) cases. Conclusions. The number of patients diagnosed with measles during the last years registered an alarming increase, especially in children under 4 year old, with a high number of complications. We consider it mandatory to apply the vaccination program to ensure an optimal vaccine coverage, useful both in stopping the current outbreak and in preventing future outbreaks.
- Subjects
MEASLES; MEASLES vaccines; VACCINATION; VIRAL disease diagnosis; VIRUS diseases; EPIDEMIOLOGY
- Publication
Romanian Journal of Infectious Diseases / Revista Romana de de Boli Infectioase, 2018, Vol 21, Issue 3, p105
- ISSN
1454-3389
- Publication type
Case Study
- DOI
10.37897/rjid.2018.3.2