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- Title
A Portable Electrochemical Dopamine Detector Using a Fish Scale-Derived Graphitized Carbon-Modified Screen-Printed Carbon Electrode.
- Authors
Yang, Feng; Han, Xiao; Ai, Yijing; Shao, Bo; Ding, Weipin; Tang, Kai; Sun, Wei
- Abstract
In this paper, a highly conductive alkali-activated graphitized carbon (a-GC) was prepared using tilapia fish scales as precursors through enzymolysis, activation and pyrolytic carbonization methods. The prepared a-GC was modified on the surface of a screen-printed carbon electrode to construct a flexible portable electrochemical sensing platform, which was applied to the differential pulse voltametric detection of dopamine (DA) using a U-disk electrochemical workstation combined with a smart phone and Bluetooth. The prepared a-GC possesses good electrical conductivity, a large specific surface area and abundant active sites, which are beneficial for the electrooxidation of DA molecules and result in excellent sensitivity and high selectivity for DA analysis. Under the optimal conditions, the oxidation peak current of DA increased gradually, with its concentrations in the range from 1.0 μmol/L to 1000.0 μmol/L, with the detection limit as low as 0.25 μmol/L (3S/N). The proposed sensor was further applied to the determination of DA in human sweat samples, with satisfactory results, which provided an opportunity for developing noninvasive early diagnosis and nursing equipment.
- Subjects
ELECTROCHEMICAL sensors; CARBON electrodes; ELECTRIC conductivity; SCALES (Fishes); NONINVASIVE diagnostic tests; SMARTPHONES
- Publication
Molecules, 2024, Vol 29, Issue 3, p744
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules29030744