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- Title
Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation.
- Authors
Münscher, Adrian; Sehner, Susanne; Taleh, Jegane; Tribius, Silke; Möckelmann, Nicolaus; Böttcher, Arne; Gulati, Amit; Dalchow, Carsten; Clauditz, Till; Knecht, Rainald
- Abstract
We discuss the clinical effectiveness and predictive value of routine panendoscopy for surveillance and follow-up of head and neck squamous cell carcinoma (HNSCC). Retrospective comparative study. Department of Otolaryngology-Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Two hundred and four HNSCC patients (follow-up between 2004 and 2007) were retrospectively evaluated. During follow-up, panendoscopy was performed routinely once a year. To avoid unnecessary procedures, we evaluated the value of radiological and clinical parameters in follow-up. On comparing normal-computerized tomography (CT) vs. abnormal CT results, a 13-fold higher frequency of recurrence (odds ratio 12.74; 95 % CI 4.22, 38.48; p < 0.001) was found. Additionally, patient medical history, clinical investigation, and recurrence pattern were significant parameters when detecting a possible recurrence. Panendoscopy could have been avoided in 40 % of patients with HNSCC (173/432). A follow-up schedule avoiding routine panendoscopy in HNSCC follow-up when the combination of diagnostic parameters is satisfactory does not influence the sensitivity or specificity of the test.
- Subjects
HEAD &; neck cancer diagnosis; ENDOSCOPY; SQUAMOUS cell carcinoma; UNIVERSITATSKLINIKUM Hamburg-Eppendorf; COMPUTED tomography; PROGNOSIS
- Publication
European Archives of Oto-Rhino-Laryngology, 2015, Vol 272, Issue 7, p1769
- ISSN
0937-4477
- Publication type
Article
- DOI
10.1007/s00405-014-3125-0