We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Duodenal Adenocarcinoma in a patient with Lynch Syndrome. A Case Report and Facts Related to Small Intestine Cancer.
- Authors
CHENG, Joyce; PATEL, Ghanshyam; KHEALNAI, Milan; KORSAPATI, Hariprasad; REDDY, Shilpa; VASAVADA, Advait; JAIN, Shikha; ADAK, Shrestha; REGASSA, Henok
- Abstract
Diagnosing small bowel cancer has been challenging due to its unusual presentation and inaccessibility on endoscopy. A 41-year-old male with a history of irritable bowel syndrome underwent esophagogastroduodenoscopy (EGD) for worsening fatigue and lightheadedness despite iron supplements therapy for low hemoglobin. Initial upper endoscopy showed esophagitis and non-bleeding duodenal bulb ulcer with exudate. Endoscopic ultrasound (EUS) with fine-needle aspiration was done due to persistent concern of malignancy and demonstrated moderately differentiated adenocarcinoma in the second portion of the duodenum. Endoscopic ultrasound with fine-needle aspiration may be a superior approach to diagnosing duodenal carcinoma than EGD alone. Small bowel cancer can be a part of the tumor spectrum of Lynch syndrome. Duodenal adenocarcinomas present at a late stage and portend a poor prognosis. We present a case of duodenal adenocarcinoma in an otherwise healthy individual emphasizing the importance of malignancy in the differential and genetic counseling in individuals with the family risk factor.
- Subjects
SMALL intestine cancer; HEREDITARY nonpolyposis colorectal cancer; ENDOSCOPIC ultrasonography; ADENOCARCINOMA; DUODENAL tumors; IRON supplements; IRRITABLE colon
- Publication
Maedica - a Journal of Clinical Medicine, 2023, Vol 18, Issue 2, p368
- ISSN
1841-9038
- Publication type
Case Study
- DOI
10.26574/maedica.2023.18.2.368