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- Title
Hidden acidosis: an explanation of acid-base and lactate changes occurring in umbilical cord blood after delayed sampling.
- Authors
Mokarami, P; Wiberg, N; Olofsson, P
- Abstract
Objective To explore the 'hidden acidosis' phenomenon, in which there is a washout of acid metabolites from peripheral tissues in both vaginal and abdominal deliveries, by investigating temporal umbilical cord blood acid-base and lactate changes after delayed blood sampling. Design Prospective comparative study. Setting University hospital. Sample Umbilical cord blood from 124 newborns. Methods Arterial and venous cord blood was sampled immediately after birth ( T0), and at 45 seconds ( T45), from unclamped cords with intact pulsations taken from 66 neonates born vaginally and 58 neonates born via planned caesarean section at 36-42 weeks of gestation. Non-parametric tests were used for statistical comparisons, with P < 0.05 considered significant. Main outcome measures Temporal changes ( T0- T45) in umbilical cord blood pH, the partial pressure of CO2 (
- Subjects
ACIDOSIS research; ACIDOSIS; CORD blood; SAMPLING (Process); BLOOD sampling; BLOOD gases
- Publication
BJOG: An International Journal of Obstetrics & Gynaecology, 2013, Vol 120, Issue 8, p996
- ISSN
1470-0328
- Publication type
Article
- DOI
10.1111/1471-0528.12234