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- Title
Lipid emulsion increases the risk of central line infection in Japanese adult inpatients: A retrospective study.
- Authors
Satoru Mitsuboshi; Hitoshi Yamada; Kazuhiko Nagai
- Abstract
Background: Several studies have suggested that lipid emulsion (LE) increases the risk of central line infection (CLI) in adult patients. However, there are limited data on the relationship between LE and CLI. Methods: We retrospectively reviewed all patients who had had a central venous catheter (CVC) inserted during a 13-month period at our institution. CLI was defined as a catheter-related local infection or a central line-associated bloodstream infection. Results: We observed 25 CLIs in 163 cases (143 patients) of CVC insertion, giving a rate of 4.6 per 1000 catheter days. In multivariate logistic regression analyses, administration of LE was associated with an increased risk of CLI (odds ratio 3.12, 95% confidence interval 1.22-8.58). Parenteral nutrition was also associated with an increased risk of CLI (odds ratio 7.86, 95% confidence interval 1.45-146.10). Conclusions: Our results suggest that administration of LE is associated with an increased risk of CLI in hospitalized Japanese adults.
- Subjects
JAPAN; BLOODBORNE infections; CATHETER-related infections; CONFIDENCE intervals; INTRAVENOUS fat emulsions; MULTIVARIATE analysis; RETROSPECTIVE studies; DATA analysis software; ODDS ratio; DISEASE risk factors
- Publication
Canadian Journal of Infection Control / Revue Canadienne de Prévention des Infections, 2017, Vol 32, Issue 2, p115
- ISSN
1183-5702
- Publication type
Article