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- Title
Fatal Acute Granulomatous Pulmonary Aspergillosis in a Healthy Subject After Inhalation of Vegetal Dust.
- Authors
Batard, E.; Renaudin, K.; Morin, O.; Desjars, P.; Germaud, P.
- Abstract
A previously healthy 28-year-old man presented a few hours after inhalation of vegetal dust with acute bilateral community-acquired pneumonia, which caused death in 10 days despite treatment with broad-spectrum antibiotics, intravenous amphotericin B, inotropic support, and mechanical ventilation. A postmortem lung biopsy indicated miliary granulomatous pulmonary aspergillosis. Six similar previously published cases of acute granulomatous pulmonary aspergillosis are reviewed. This entity in adulthood may reveal a defect in neutrophil or macrophage function, such as late-onset chronic granulomatous disease.
- Subjects
PULMONARY aspergillosis; FUNGAL lung diseases; DUST; ANTIBIOTICS; AMPHOTERICIN B; CHRONIC granulomatous disease
- Publication
European Journal of Clinical Microbiology & Infectious Diseases, 2003, Vol 22, Issue 6, p357
- ISSN
0934-9723
- Publication type
Article
- DOI
10.1007/s10096-003-0939-x