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- Title
Production of no-carrier-added radiobromine: new nickel selenide target and optimized separation by dry distillation.
- Authors
Breunig, Katharina; Spahn, Ingo; Spellerberg, Stefan; Coenen, Heinz H.
- Abstract
Nickel(II) selenide (NiSe) was investigated as a new high-current target material for cyclotron production of radiobromine, as it contains a higher amount of selenium and has a lower melting point than the widely used Cu2Se. Using a slanted target system, NiSe was successfully tested up to beam currents of 16 μA so far. With regard to the isolation of no-carrier-added (n.c.a.) radiobromide from the target material, an improved dry distillation device with high yields of 76% - 86% was developed. The implementation of a special custom-made quartz funnel decreased the dead volume of the apparatus and a quartz capillary for trapping the radiobromine allowed to concentrate the radioactivity in a small volume of less than 100 μL of 0.1 M NaOH, ready for immediate subsequent radiosyntheses. Thus, the new apparatus improves the handling of the isolation procedure and the radioactive product. The radiochemical purity of the resulting solution of n.c.a. [*Br]bromide was verified by radio-IC where no other species were detected.
- Subjects
MOLECULAR distillation; RADIOCHEMICAL separation; CYCLOTRONS; RADIOACTIVITY measurements; POSITRON emission tomography; BROMIDE ions; RADIONUCLIDIC purity
- Publication
Radiochimica Acta, 2015, Vol 103, Issue 5, p397
- ISSN
0033-8230
- Publication type
Article
- DOI
10.1515/ract-2014-2366