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- Title
Phytochemical Screening and Antibacterial Activity Of Polyalthia Longifolia Crude Extracts.
- Authors
Uzama, D.; David, M. B.; Ahmadu, R.; Thomas, S. A.
- Abstract
Objective: To study of the antibacterial activities of the methanolic, ethanolic, ethylacetate and petroleum ether extracts of the leaves of Polyalthia longifolia Methods :The plant Polyalthia longifolia has some medicinal values and is used in the treatment of some diseases. The chemical agents possessed by the various parts of the plant are believed to be responsible for their medicinal values. The crude extracts of the leaves of Polyalthia longifolia were subjected to phytochemical investigations using standard methods. The tests conducted indicated the presence of alkaloids, tannins, saponins and glycosides. A study of the antibacterial activities of the methanolic, ethanolic, ethylacetate and petroleum ether extracts of the leaves of Polyalthia longifolia was carried out using agar well diffusion method. Results:The study indicated that the extracts inhibited Bacillus subtilis and Staphylococcus aureus at 25mg/ml.The minimum inhibitory concentrations of the crude extracts were determined for the various organisms which ranged between 0.01 and 0.5mg/ml, while the minimum bactericidal concentrations ranged between 0.01 and 1.3mg/ml. Conclusion:Polyalthia longifolia could be a potential source of antimicrobial agents.
- Subjects
PLANT diseases; MEDICAL research; ORGANIC compounds; STAPHYLOCOCCUS; GLUCOSIDES
- Publication
Asian Journal of Pharmaceutical & Biological Research (AJPBR), 2011, Vol 1, Issue 4, p480
- ISSN
2231-2218
- Publication type
Article