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- Title
The analysis of the termination of pregnancies at and after ten weeks of gestation - a monocenter study.
- Authors
Baran, Şafak Yılmaz; Alemdaroğlu, Songül; Durdağ, Gülşen Doğan; Kalaycı, Hakan; Çelik, Zerrin Yılmaz
- Abstract
Objective: We aimed to manage the termination of pregnancies, which were performed at and after 10 weeks of gestation in our clinic, better and to develop appropriate approaches for them by investigating the indications and obstetric characteristics of these cases. Methods: The maternal data, obstetric characteristics and indications of 379 cases whose termination procedures were performed in our clinic between January 2012 and January 2019 were evaluated. The indications were grouped as maternal reasons, amniotic fluid anomalies, and isolated structural, multiple congenital and genetic disorders. The groups were classified according to their characteristics and they were compared among each other. Results: The mean age was 30.2±6, the mean week of gestation was 17.4±3.5, and mean termination duration was 16.4±14.5 hours. The most common reason for termination was amniotic fluid anomalies (n=126, 33.2%). Among fetal reasons, the most common one was isolated structural anomalies (n=114, 30.1%). The anomalies of central nervous system were the most common isolated structural anomalies (n=60, 15.8%). Of 379 termination cases, 25 (6.6%) were caused by maternal reasons. The rates of requesting invasive examination for genetic disorders and of performing the examination were 49.6% (n=197) and 31.7% (n=120), respectively. Chromosomal anomalies were found in 69 (18.2%) cases, with trisomy 21 being the most common anomaly (n=39, 55.7%). It was found out that chromosomal anomalies were identified in more advanced maternal ages and at earlier weeks of gestation. On the other hand, isolated structural and multiple congenital anomalies (cardiac and urogenital anomalies in particular) were identified at younger ages and further weeks of gestation (maternal age, p=0.002; week of gestation, p<0.001). Conclusion: The analysis of fetal and maternal reasons and termination complications in the management of termination cases will serve as an example for the management of diagnosis and termination processes of following pregnancies. We believe that considering the ethical, psychological and legal aspects of the terminations of pregnancies will be beneficial in developing standard approaches for this matter with the help of collaboration between families and physicians.
- Subjects
ABORTION complications; DURATION of pregnancy; OBSTETRICS; CHROMOSOME abnormalities; GENETIC disorder diagnosis
- Publication
Perinatal Journal / Perinatoloji Dergisi, 2019, Vol 27, Issue 1, p14
- ISSN
1300-5251
- Publication type
Article
- DOI
10.2399/prn.19.0271003