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- Title
In vitro evaluation of antimicrobial and antioxidant activities of methanolic extract of Jasminum humile Leaves
- Authors
Nain, Parminder; Kumar, Ashok; Sharma, Sunil; Nain, Jaspreet
- Abstract
Abstract: Objective: To evaluate in vitro antimicrobial and antioxidant activities of methanolic extract of Jasminum humile (J. humile) leaves extract. Method: Methanolic extract of J. humile was evaluated for its antimicrobial activity by using agar well diffusion method & their possible antioxidant assay by two complementary test systems, namely DPPH and hydrogen peroxide scavenging activity. These various antioxidant activities were compared to standard antioxidants such as ascorbic acid for both the tests. Results: In the DPPH & hydrogen peroxide scavenging activity, the IC50 value of methanol extract was 70.43 μg/mL & 60.79 μg/mL respectively. Further, the extract showed inhibitory activity for Gram-positive and negative bacteria at different concentrations. The maximum antibacterial activity of extract was exhibited against Staphylococcus aureus (S. aureus) at concentration 50 mg/mL when compared with ciprofloxacin Conclusions: These results clearly indicate that J. humile is effective in scavenging free radicals and has the potential to be a powerful antioxidant. Thus, the results obtained in the present study indicate that J. humile leaves extract could be considered as a potential source of natural antioxidants and that could be used as an effective source against bacterial diseases.
- Subjects
ANTI-infective agents; ANTIOXIDANTS; METHANOL; PLANT extracts; LEAVES; JASMINE; VITAMIN C
- Publication
Asian Pacific Journal of Tropical Medicine, 2011, Vol 4, Issue 10, p804
- ISSN
1995-7645
- Publication type
Article
- DOI
10.1016/S1995-7645(11)60198-3