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- Title
Elemene treatment for NSCLC with multiple CNS metastases: a case report and literature review.
- Authors
Han, Yushan; Zhang, Xia; Lu, Yishan; Dong, Yan; Fu, Hong; Zhang, Bin; Gao, Yajie
- Abstract
CNS metastases are common in patients with non-small-cell lung cancer (NSCLC) and is associated with poor prognosis. In NSCLC patients with EGFR mutations, and ALK fusion oncogene, chemotherapy is ineffective; however, targeted and pulse therapies may be used as alternative treatment options. Elemene can cross the blood–brain barrier and enter the brain tissue. In this paper, treatment consisting of elemene injections in a case of NSCLC with brain metastases, spinal metastases and a possible complication of leptomeningeal metastases is reported, and the efficacy of elemene in treating NSCLC with CNS metastases was investigated.
- Subjects
CENTRAL nervous system; CANCER chemotherapy; MENINGEAL cancer; INTRACEREBRAL transplantation; COMPUTED tomography
- Publication
OncoTargets & Therapy, 2018, Vol 11, p6377
- ISSN
1178-6930
- Publication type
Article
- DOI
10.2147/OTT.S160970