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- Title
ANTIMICROBIAL RESISTANCE OF ESCHERICHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTIONS.
- Authors
CRACIUNESCU, MIHAELA; LICKER, MONICA; MUNTEAN, DELIA; HOGEA, ELENA; BERCEANUVADUVA, DELIA; DUGAESESCU, DORINA; SERBAN, D.; POPA, MIHAELA; PILUT, C.; HORHAT, F.; TATU, CARMEN; MOLDOVAN, ROXANA
- Abstract
Purpose: For nosocomial urinary infections (NUI) monitoring, samples were taken between January 2008 and January 2009, from 629 patients hospitalsed in the Obstetrics and Gynecology Timisoara Hospital. Methods: The Gram-negative Germs were identified at the specie level by biochemical testing using the API ID 32 E galleries (bioMerieux) and their antimicrobial resistance was determined by agar mini API microdilution and the Kirby-Bauer disk diffusion (on standardized subculture) methods. Results: From the totalnumber of 207 positive urocultures were isolated some strains with high nosocomial potential and the leader were E. coli, with 130 strains. Unfortunately, only 23.84% from the E. coli isolated strains kept unaffected their natural sensibility to the antimicrobial therapy. The penicillinase producing strains represented 63.07 % and the CAZA and CHN strains represented 6.91 %. The ESBL producing strains (3.07%) associated aminoglycozides and fluoroquinolones resistance Conclusions: The UTI, especially the NUI, become a health problem due to the increasing number of cases and the difficulty of treatment caused by the multiresistance to antimictobial treatment. The increased number of strains with acquired resistance to the antimicrobial therapy found by the present research study is underlining the importance of permanent and systematic monitoring of the phenomenon.
- Subjects
DRUG resistance in microorganisms; ESCHERICHIA coli; URINARY tract infections; DILUTION; NOSOCOMIAL infections; BETA lactamases; AMINOGLYCOSIDES; FLUOROQUINOLONES; AMOXICILLIN
- Publication
Physiology / Fiziologia, 2009, Vol 19, Issue 4, p18
- ISSN
1223-2076
- Publication type
Article