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- Title
Uterine angioleiomyoma in an African green monkey ( Chlorocebus aethiops sabaeus).
- Authors
Valentine, Matthew John; Beierschmitt, Amy; DeLay, Josepha; Callanan, John Joseph
- Abstract
Background A uterine neoplasm was observed, as an incidental finding, during post-mortem examination of a 26-year-old female multiparous African green monkey ( Chlorocebus aethiops sabaeus). The intramural, expansile, 2 to 3 cm well-demarcated, dark-red, nodular neoplasm was located on the anterior uterine body (corpus) wall. Methods The mass was examined by light microscopy and by immunohistochemistry. Results The mass was confirmed as a cavernous uterine angioleiomyoma (syn. vascular leiomyoma) characterized by abundant intratumoural vasculature lined by Factor VIII-positive endothelial cells and surrounded by smooth muscle actin-positive cell proliferations. Conclusion Angioleiomyoma sharing the characteristics of intramural human cavernous uterine angioleiomyoma should be considered in the differential diagnosis of uterine tumours in non-human primates.
- Subjects
UTERINE fibroids; CERCOPITHECUS aethiops; MAMMAL reproduction; MONKEYS; UTERINE cancer; MICROSCOPY; IMMUNOHISTOCHEMISTRY
- Publication
Journal of Medical Primatology, 2017, Vol 46, Issue 1, p9
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/jmp.12248