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- Title
Gastric wall uptake and attenuation artifact in 99m-Tc sestamibi SPECT: Hold the proton pump inhibitors!
- Authors
AlJaroudi, Wael
- Abstract
Indeed, Goel et al evaluated 121 patients (91 women) undergoing single-day rest/stress 99m-Tc-sestamibi SPECT (26 taking PPIs, 14 H2-receptor antagonists and 81 neither).[6] GWU was strongly associated with prolonged use of PPIs (Chi square = 51.9, I P i <.0001) but not with H2-receptor antagonists. Patients on PPIs were more likely to have clinically relevant stomach wall uptake (score 2 to 3) as compared to patients not using PPIs (22% vs 7%, I P i =.017), and irrespective of gastric symptoms.[10] Therefore, it is important to elicit a history of prolonged PPI use, anticipate the possibility of increased stomach wall activity, which can confound the image quality and diagnostic interpretation. Should patients hold proton pump inhibitors prior to (82)rubidium positron emission tomography myocardial perfusion imaging?.
- Publication
Journal of Nuclear Cardiology, 2022, Vol 29, Issue 4, p1562
- ISSN
1071-3581
- Publication type
Article
- DOI
10.1007/s12350-021-02528-7