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- Title
Acquired idiopathic generalized anhidrosis with isolated sudomotor neuropathy.
- Authors
Miyazoe, Seiji; Matsuo, Hidenori; Ohnishi, Akio; Tajima, Fumihiro; Fujishita, Satoshi; Ichinose, Katsuhiro; Shibuya, Noritoshi
- Abstract
The pathogenesis and underlying lesion of acquired idiopathic generalized anhidrosis (AIGA) are apparently heterogeneous. We report a patient with AIGA in whom the eccrine glands were histologically normal. However, electron microscopic examination showed markedly low numbers of nerve terminals and unmyelinated axons associated with the eccrine glands. Our laboratory investigations suggest that degeneration of postganglionic sympathietic cholinergic nerve may be the underlying pathogenetic mechanism of anhidrosis in this patient.
- Publication
Annals of Neurology, 1998, Vol 44, Issue 3, p378
- ISSN
0364-5134
- Publication type
Article
- DOI
10.1002/ana.410440314