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- Title
Prediction models for postoperative uncontrolled chronic rhinosinusitis in daily practice.
- Authors
Tao, Xiaoyao; Chen, Fenghong; Sun, Yueqi; Wu, Shulian; Hong, Haiyu; Shi, Jianbo; Xu, Rui
- Abstract
<bold>Objectives/hypothesis: </bold>The European Position Paper on Rhinosinusitis and Nasal Polyps proposes an assessment of clinical control of chronic rhinosinusitis (CRS). However, there are limited data about the percentage of postoperative control, and no prediction models for uncontrolled CRS have been reported. The aim of the study was to develop prediction models for postoperative uncontrolled CRS.<bold>Study Design: </bold>Retrospective case series.<bold>Methods: </bold>Patients (n = 136) who had undergone endoscopic sinus surgery at least 1 year prior to the study were recruited to assess the clinical control. Risk factors were determined by logistic models and presented as odds ratio (OR) with a 95% confidence interval. Receiver operating characteristics curves were constructed to set the cutoff points and create predictive models.<bold>Results: </bold>Approximately 47.8% of patients had controlled, 22.1% partially controlled, and 30.1% uncontrolled CRS. Univariate regression models revealed the risk factors for uncontrolled CRS: tissue eosinophilia, blood eosinophilia, high computed tomography (CT) score, bilateral disease, asthma, and allergic rhinitis. Multiple regression models found tissue eosinophil ratio >0.206 (OR: 12.96, P = .001) or blood eosinophil ratio >0.025 (OR: 4.56, P = .003), Lund-Mackay (LM) score ≥ 15 (OR: 15.50, P < .001) and CT ethmoid (E) score ≥ maxillary (M) score (OR: 3.51, P = .037) were independent risk factors. We generated a pathological model (tissue eosinophil ratio and LM score) and a clinical model (blood eosinophil ratio, LM score and E ≥ M score) to categorize CRS into mild, moderate, and severe.<bold>Conclusions: </bold>This research provides simplified and efficient prediction models for uncontrolled CRS. It may help otolaryngologists to predict the prognosis before surgery in daily practice.<bold>Level Of Evidence: </bold>2b Laryngoscope, 128:2673-2680, 2018.
- Subjects
SINUSITIS; COMPUTED tomography; ASTHMA; ALLERGIC rhinitis; EOSINOPHILIA; CHRONIC diseases; COMPARATIVE studies; DECISION making; RESEARCH methodology; MEDICAL cooperation; MEDICAL specialties &; specialists; NASAL polyps; POSTOPERATIVE period; REFERENCE values; RESEARCH; RESEARCH funding; RHINITIS; SURGICAL complications; LOGISTIC regression analysis; EVALUATION research; RETROSPECTIVE studies; RECEIVER operating characteristic curves; ODDS ratio
- Publication
Laryngoscope, 2018, Vol 128, Issue 12, p2673
- ISSN
0023-852X
- Publication type
journal article
- DOI
10.1002/lary.27267