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- Title
Rim15 and Sch9 kinases are involved in induction of autophagic degradation of ribosomes in budding yeast.
- Authors
Waliullah, Talukdar Muhammad; Yeasmin, Akter Mst; Kaneko, Atsuki; Koike, Naoki; Terasawa, Mashu; Totsuka, Takaya; Ushimaru, Takashi
- Abstract
Autophagic degradation of ribosomes is promoted by nutrient starvation and inactivation of target of rapamycin complex 1 (TORC1). Here we show that selective autophagic degradation of ribosomes (called ribophagy) after TORC1 inactivation requires the specific autophagy receptor Atg11. Rim15 protein kinase upregulated ribophagy, while it downregulated non-selective degradation of ribosomes.
- Subjects
RIBOSOMES; BIODEGRADATION; TOR proteins; PHYSIOLOGY
- Publication
Bioscience, Biotechnology & Biochemistry, 2017, Vol 81, Issue 2, p307
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2016.1234928