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- Title
Three Dimensional Power Doppler evaluation of human endometrium after administration of oxytocine receptor antagonist (OTRa) in an IVF program.
- Authors
Kalmantis, Konstantinos; Loutradis, Dimitrios; Lymperopoulos, Elias; Beretsos, Panagiotis; Bletsa, Ritsa; Antsaklis, Aris
- Abstract
Purpose: To compare endometrial and subendometrial morphological changes and vascularity as measured by 3D Power Doppler sonography, based on a specific scoring system between women subjected or not to oxytocine receptor antagonist (OTRa) during IVF cycles. Methods: Twenty-six women were divided into groups according to OTRa (Atosiban tractocide) administration. The first group (control n = 13 women) was examined with 3D Power Doppler 3 days after embryo transfer. The second group ( n = 13 women) was administered 7.5 mg intravenous tractocide 2 days after embryo transfer and a 3D Power Doppler was performed after a day. Results: The control group presented the following ultrasonographic characteristics: (a) echogenic endometrium in all cases, (b) endometrial thickness >7 mm in all cases (84.6%), (c) endometrial volume >2.31 cm in 5 cases (38.5%), (d) abnormal sub-endometrial halo in 3 cases (23.1%), (e) endometrial blood flow in 6 cases (46.2%) and (f) complex vessel's architecture in 2 cases (15.4%). In women who underwent OTRa administration were observed: (a) echogenic endometrium in 1 case (7.7%), triple line endometrium in 12 cases (92.3%), (b) endometrial thickness >7 mm in all cases, (c) endometrial volume >2.31 cm in 11 cases (84.6%), (d) abnormal sub-endometrial halo in 3 cases (23.1%), (e) endometrial blood flow in 11 cases (84.6%) and (f) complex vessel's architecture in 6 cases (46.2%). Conclusions: Women who have taken OTRa presented an endometrium with characteristics more predictive of implantation.
- Subjects
ENDOMETRIUM; OXYTOCIN; EMBRYO transfer; DOPPLER ultrasonography; MENSTRUAL cycle; BLOOD flow; WOMEN'S health
- Publication
Archives of Gynecology & Obstetrics, 2012, Vol 285, Issue 1, p265
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-011-2019-2