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- Title
Introduction.
- Authors
Alber, Mark; Godin, Christophe; Maini, Philip K.; Merks, Roeland; Mjolsness, Eric
- Abstract
Highlights from the article: Modeling in developmental biology differs from many other fields of mathematical biology in that the background topology and geometry on which the dynamics of patterning and information processing play out are themselves dynamic. In this framework, CIL is shown to be an emergent phenomenon arising through indirect cell-cell interactions via the substrate, rather than the commonly imposed direct cell-cell interaction rules. Interestingly, the empirically obtained expression pattern of WUS, combined with the assumed expansion directions of the cells, was sufficient to predict the progressive bulging of the SAM and its shape as well as its maintenance.
- Subjects
COMPUTATIONAL biology; DEVELOPMENTAL biology; STEM cell niches; PLANT morphogenesis
- Publication
Bulletin of Mathematical Biology, 2019, Vol 81, Issue 8, p3214
- ISSN
0092-8240
- Publication type
Editorial
- DOI
10.1007/s11538-019-00649-2