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- Title
Associated ileocaecal location is a marker for greater severity of low rectal endometriosis.
- Authors
Marcellin, L; Leconte, M; Gaujoux, S; Santulli, P; Borghese, B; Chapron, C; Dousset, B
- Abstract
<bold>Objective: </bold>To determine whether ileocaecal endometriosis (ICE) is a marker for low rectal endometriosis (LRE) severity.<bold>Design: </bold>Retrospective cohort study.<bold>Setting: </bold>France.<bold>Population and Sample: </bold>Analysis of 375 colorectal resections performed in women undergoing complete surgery for LRE from January 1995 to December 2015 in a university centre for endometriosis.<bold>Methods: </bold>Univariate and multivariate analysis of anatomical, postoperative clinical, and long-term outcomes according to presence of ICE.<bold>Main Outcomes and Measures: </bold>Mean number and type of deep infiltrating endometriosis (DIE) lesions, the existence of an associated endometrioma, and mean total American Society for Reproductive Medicine (ASRM) score.<bold>Results: </bold>The prevalence of ICE was 25.6%. Primary end-point data showed that women with ICE had a significantly higher adjusted number of DIE lesions (OR = 1.43, 95% CI 1.02-3.03; P = 0.048), higher prevalence of endometriomas (OR = 1.91, 95% CI 1.04-3.51; P = 0.044), more associated DIE sigmoid lesions (OR = 2.12, 95% CI 1.07-3.91; P = 0.025), and a higher mean total ASRM score (OR = 2.07, 95% CI 1.12-4.14; P = 0.025). Women with ICE resected during the surgical procedure for LRE did not have more adverse postoperative clinical outcomes than ICE-negative patients.<bold>Conclusion: </bold>Ileocaecal endometriosis was significantly associated with greater LRE severity. In a complete surgical resection strategy, combining resection of ICE and LRE did not appear to increase postoperative rates of complications, morbidity or recurrence, nor did it seem to impair long-term clinical outcomes.<bold>Tweetable Abstract: </bold>In women with low rectal endometriosis, 25% have an associated ileocaecal location that is a marker for severity.
- Subjects
FRANCE; ENDOMETRIOSIS; REPRODUCTIVE health; SURGICAL complications; UNIVARIATE analysis; MULTIVARIATE analysis
- Publication
BJOG: An International Journal of Obstetrics & Gynaecology, 2019, Vol 126, Issue 13, p1600
- ISSN
1470-0328
- Publication type
journal article
- DOI
10.1111/1471-0528.15901