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- Title
The Effects of Smokeless Tobacco "Maras Powder" on Homocysteine and Cardiovascular Risk.
- Authors
Baylan, Filiz Alkan; Yarar, Esra; Cansun, Funda; Doğaner, Adem; Sökmen, Gülizar
- Abstract
Introduction: This study aims to investigate the relationship between smokeless tobacco (Maras powder) and cigarette consumption with homocysteine, Paraoxonase-1 (PON-1), Arylesterase (ARE), and Lipoprotein-a (Lp (a)), which are known as risk factors for cardiovascular diseases. Materials and Methods: The individuals included in the study were divided into three groups as Maras powder users (n = 38), cigarette smokers (n = 38), and healthy volunteers who did not use either tobacco group (n = 38). Serum homocysteine, PON-1, ARE, and Lp (a) levels of all participants were examined. Results: When the groups are compared, the highest homocysteine level was in the Maras powder group. While the difference between the control group and the Maras powder group was statistically significant, the difference between the control and smokers groups was statistically insignificant. Although PON values were lower in both the Maras powder and smokers groups than the control group, the difference was significant only in the smoking group. ARE was significantly lower, and Lp (a) was significantly higher in both tobacco smokers groups compared to the control group. Conclusion: Serum homocysteine levels increase in both Maraş powder users and smokers. Moreover; Decreased PON-1 and ARE levels in smokers, decreased ARE levels in Maraş powder users show that Maraş powder use has side effects at least as much as cigarettes.
- Subjects
TOBACCO use; SMOKELESS tobacco; HOMOCYSTEINE; PARAOXONASE; CARDIOVASCULAR diseases
- Publication
Sakarya Tıp Dergisi, 2023, Vol 13, Issue 2, p197
- ISSN
2146-2585
- Publication type
Article
- DOI
10.31832/smj.1159218