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- Title
Regional differences in the prevalence of known Type 2 diabetes mellitus in 45-74 years old individuals: Results from six population-based studies in Germany (DIAB-CORE Consortium).
- Authors
Schipf, S.; Werner, A.; Tamayo, T.; Holle, R.; Schunk, M.; Maier, W.; Meisinger, C.; Thorand, B.; Berger, K.; Mueller, G.; Moebus, S.; Bokhof, B.; Kluttig, A.; Greiser, K. H.; Neuhauser, H.; Ellert, U.; Icks, A.; Rathmann, W.; Völzke, H.
- Abstract
Diabet. Med. 29, e88-e95 (2012) Abstract Aim In Germany, regional data on the prevalence of Type 2 diabetes mellitus are lacking for health-care planning and detection of risk factors associated with this disease. We analysed regional variations in the prevalence of Type 2 diabetes and treatment with antidiabetic agents. Methods Data of subjects aged 45-74 years from five regional population-based studies and one nationwide study conducted between 1997 and 2006 were analysed. Information on self-reported diabetes, treatment, and diagnosis of diabetes were compared. Type 2 diabetes prevalence estimates (95% confidence interval) from regional studies were directly standardized to the German population (31 December 2007). Results Of the 11 688 participants of the regional studies, 1008 had known Type 2 diabetes, corresponding to a prevalence of 8.6% (8.1-9.1%). For the nationwide study, a prevalence of 8.2% (7.3-9.2%) was estimated. Prevalence was higher in men (9.7%; 8.9-10.4%) than in women (7.6%; 6.9-8.3%). The regional standardized prevalence was highest in the east with 12.0% (10.3-13.7%) and lowest in the south with 5.8% (4.9-6.7%). Among persons with Type 2 diabetes, treatment with oral antidiabetic agents was more frequently reported in the south (56.9%) and less in the northeast (46.0%), whereas treatment with insulin alone was more frequently reported in the northeast (21.6%) than in the south (16.4%). Conclusion The prevalence of known Type 2 diabetes showed a southwest-to-northeast gradient within Germany, which is in accord with regional differences in the distribution of risk factors for Type 2 diabetes. Furthermore, the treatment with antidiabetic agents showed regional differences.
- Subjects
GERMANY; CONFIDENCE intervals; EPIDEMIOLOGY; TYPE 2 diabetes; POPULATION geography; RESEARCH funding; SEX distribution; DATA analysis; DISEASE prevalence; DATA analysis software
- Publication
Diabetic Medicine, 2012, Vol 29, Issue 7, pe88
- ISSN
0742-3071
- Publication type
Article
- DOI
10.1111/j.1464-5491.2012.03578.x