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- Title
Treatment de‐intensification for low‐risk biochemical recurrence after radical prostatectomy: rational or risky?
- Authors
Roberts, Matthew J.; Hruby, George; Kneebone, Andrew; Martin, Jarad M.; Williams, Scott G.; Frydenberg, Mark; Murphy, Declan G.; Namdarian, Ben; Yaxley, John W.; Hofman, Michael S.; Davis, Ian D.; Emmett, Louise
- Abstract
1 Table Comparison of salvage radiation treatment and surveillance as management strategies for low-risk biochemical recurrence with negative prostate-specific membrane antigen positron emission tomography/CT. Abbreviations ADT androgen deprivation therapy EAU European Association of Urology PET positron emission tomography PSMA prostate-specific membrane antigen RT radiation therapy Biochemical recurrence, or first detection of measurable serum PSA after radical prostatectomy, occurs in approximately one-third of patients [[1]] and is often the first indicator of residual or relapsed prostate cancer. As most potential sources of biochemical recurrence are located in the pelvis, treatment of biochemical recurrence largely relies on salvage radiation therapy (RT), including prostate bed/fossa with or without pelvic lymph node RT, sometimes with androgen deprivation therapy (ADT).
- Subjects
RADICAL prostatectomy; PROSTATE cancer; UROLOGISTS; WATCHFUL waiting; POSITRON emission tomography; SCHOLARSHIPS
- Publication
BJU International, 2023, Vol 132, Issue 2, p146
- ISSN
1464-4096
- Publication type
Article
- DOI
10.1111/bju.16086