Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleAdvocating for Demonstration of Disease Modification—Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly?AuthorsPlanche, Vincent; Villain, NicolasAbstractThis Viewpoint discusses the benefits of clinical trials with a delayed-start design and analysis of downstream biomarkers to examine whether antimyeloid immunotherapy changes the course of early Alzheimer disease.PublicationJAMA Neurology, 2023, Vol 80, Issue 7, p659ISSN2168-6149Publication typeOpinionDOI10.1001/jamaneurol.2023.0815