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- Title
Recent advances in entirely hand-held ionization sources for mass spectrometry.
- Authors
Fan, Jinghan; Ma, Wenbo; Yu, Yile; Li, Yuze; Nie, Zongxiu
- Abstract
Ambient ionization mass spectrometry (AIMS) has been developing explosively since its first debut. The ionization process was hence able to be achieved under atmospheric pressure, facilitating on-site field analysis in a variety of areas, such as clinical diagnosis, metabolic phenotyping, and surface analysis. As part of the ambitious goal of making MS a general device that can be used in everyday life, lots of efforts have been paid to miniaturize the ionization source. This review discusses avant-garde sources that could be entirely hand-held without any accessories. The structure and applications of the devices are described in detail as well. They could be expediently used in real-time and on-site analysis, presenting a great future potential for the routinizing of MS.
- Subjects
CROWDSOURCING; MASS spectrometry; SURFACE analysis; ATMOSPHERIC pressure
- Publication
Analytical & Bioanalytical Chemistry, 2024, Vol 416, Issue 9, p2057
- ISSN
1618-2642
- Publication type
Article
- DOI
10.1007/s00216-023-05022-w