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- Title
Role of micro‐RNAs associated with adipose‐derived extracellular vesicles in metabolic disorders.
- Authors
Payet, Thomas; Gabinaud, Elisa; Landrier, Jean‐François; Mounien, Lourdes
- Abstract
Summary: Micro‐RNAs have emerged as important actors in the onset of metabolic disorders including obesity or type 2 diabetes. Particularly, several micro‐RNAs are known to be key modulators of lipid metabolism, glucose homeostasis, or feeding behavior. Interestingly, the role of extracellular vesicles containing micro‐RNAs, especially adipose‐derived extracellular vesicles, are well‐documented endocrine signals and disease biomarkers. However, the role of adipose‐derived extracellular vesicles on the different tissues is different and highly related to the micro‐RNA content. This review provides recent data about the potential involvement of adipose‐derived extracellular vesicle‐containing micro‐RNAs in metabolic diseases.
- Subjects
EXTRACELLULAR vesicles; MICRORNA; METABOLIC disorders; TYPE 2 diabetes; ENDOCRINE diseases
- Publication
Obesity Reviews, 2024, Vol 25, Issue 7, p1
- ISSN
1467-7881
- Publication type
Article
- DOI
10.1111/obr.13755