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- Title
Commentary on ‘Resveratrol commonly displays hormesis: Occurrence and biomedical significance’.
- Authors
Young, Jette F.; Bhattacharya, Sumangala
- Abstract
The lead article ‘‘Resveratrol commonly displays hormesis: occurrence and biomedical significance’’ underlines the hormetic response of resveratrol in many disease models. This commentary suggests that the greatest potential advantage of the positive effects of resveratrol for the broad population would be as prevention of disease development through oral administration in its original food matrix, although it still remains important to investigate the extent of resveratrol administration giving maximum beneficial effect for biomedical purposes. In relation to resveratrol ‘‘supplementation’’ through its natural environment further investigation of the impact of co-occurring bioactive compounds and matrix effects on hormetic responses of resveratrol is necessary for revealing mechanisms behind e.g. the ‘‘French paradox’’.
- Subjects
RESVERATROL; HORMESIS; PHYTOCHEMICALS; BIOACTIVE compounds; FRENCH Paradox; EXPERIMENTAL toxicology; THERAPEUTICS
- Publication
Human & Experimental Toxicology, 2010, Vol 29, Issue 12, p1032
- ISSN
0960-3271
- Publication type
Opinion
- DOI
10.1177/0960327110383636