We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A New Phenothiazine-Based Fluorescent Sensor for Detection of Cyanide.
- Authors
Li, Yulei; Zhou, Chen; Li, Jiaxin; Sun, Jing
- Abstract
A new fluorescent sensor for the detection of CN− was developed based on the conjugation of phenothiazine fluorophore and benzofuran unit. By the nucleophilic attacking of CN− to the fluoroacetylamino group in the sensor, the additional reaction of CN− and carbonyl group induced the ICT (intramolecular charge transfer) effect in the molecule and caused the fluorescence quenching sensor. The titration experiments show that the sensor has good sensitivity, selectivity and quick response for CN−. In addition, the fluorescent detection of CN− in the living cell and zebrafish experiments demonstrated the value of the sensor in tracing the CN− in biological systems.
- Subjects
CYANIDES; INTRAMOLECULAR charge transfer; FLUORESCENCE quenching; DETECTORS; CARBONYL group; PHENOTHIAZINE
- Publication
Biosensors (2079-6374), 2024, Vol 14, Issue 1, p51
- ISSN
2079-6374
- Publication type
Article
- DOI
10.3390/bios14010051