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- Title
Impact of the Kidney Allocation Revision on Access to Kidney Transplantation and Outcomes in the United States.
- Authors
Akinyemi, Oluwasegun A.; Weldeslase, Terhas A.; Odusanya, Eunice A.; Hughes, Kakra; Cornwell, Edward E.; Callender, Clive O.
- Abstract
Background: The 2014 Kidney Allocation System (KAS) revision aimed to enhance equity in organ allocation and improve patient outcomes. This study assesses the impacts of the KAS revision on renal transplantation demographics and outcomes in the United States. Methods: We conducted a retrospective study utilizing the Organ Procurement and Transplantation Network/Scientific Registry of Transplant Recipients (OPTN/SRTR) database from 1998 to 2022. We compared recipient and donor characteristics, and outcomes (graft failure and recipient survival) pre- and post-KAS revision. Results: Post-KAS, recipients were significantly older (53 vs 48, P <.001) with an increase in Medicaid beneficiaries (7.3% vs 5.5%, P <.001). Despite increased graft survival, HR =.91 (95% CI 0.80-.92, P <.001), overall recipient survival decreased, HR = 1.06 (95% CI 1.04-1.09, P <.001). KAS revision led to greater racial diversity among recipients and donors, enhancing equity in organ allocation. However, disparities persist in graft failure rates and recipient survival across racial groups. Discussion: The 2014 Kidney Allocation System revision has led to important changes in the renal transplantation landscape. While progress has been made towards increasing racial equity in organ allocation, further refinements are needed to address ongoing disparities. Recognizing the changing patient profiles and socio-economic factors will be crucial in shaping future policy modifications.
- Subjects
UNITED States; KIDNEY transplantation; KIDNEYS; TRANSPLANTATION of organs, tissues, etc.; MEDICAID beneficiaries; GRAFT survival
- Publication
American Surgeon, 2024, Vol 90, Issue 7, p1886
- ISSN
0003-1348
- Publication type
Article
- DOI
10.1177/00031348241241628