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- Title
Association of Family History With Cancer Recurrence and Survival Among Patients With Stage III Colon Cancer.
- Authors
Chan, Jennifer A.; Meyerhardt, Jeffrey A.; Niedzwiecki, Donna; Hollis, Donna; Saltz, Leonard B.; Mayer, Robert J.; Thomas, James; Schaefer, Paul; Whittom, Renaud; Hantel, Alexander; Goldberg, Richard M.; Warren, Robert S.; Bertagnolli, Monica; Fuchs, Charles S.
- Abstract
The article presents a study seeking to determine the influence family history of colorectal cancer has on cancer recurrence and survival rates among colon cancer patients. The design and setting of the prospective observational study involving over a thousand stage III colon cancer patients are detailed. The outcomes measured include disease-free survival, recurrence-free survival, and overall survival in relation to the presence of a family history of colorectal cancer. Results suggest a significant reduction in cancer recurrence and death among colon cancer patients receiving adjuvant chemothrapy who had a family history of colorectal cancer.
- Subjects
COLON cancer patients; HUMAN heredity; CANCER relapse; FAMILY history (Sociology); MORTALITY; HUMAN genetics
- Publication
JAMA: Journal of the American Medical Association, 2008, Vol 299, Issue 21, p2515
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.299.21.2515