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- Title
Cloning by numbers.
- Authors
Houdebine, Louis-Marie
- Abstract
Reports on new technique in mouse cloning which leads to higher birthrates. Association of cloned embryos with low rates of pregnancy and birth; Explanation of simple procedure of embryo aggregation improving cloning outcomes; Results showing cloned mouse blastocysts with abnormally low numbers of cells and aggregation of two embryos compensating for deficiency; Correction of various defects in embryos by added blastomeres; Reprogramming of somatic cell genome a more complex process than anticipated.
- Subjects
CLONING; BLASTOGENESIS (Embryology); CORRECTIONS (Criminal justice administration); SOMATIC cells; LABORATORY mice
- Publication
Nature Biotechnology, 2003, Vol 21, Issue 12, p1451
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt1203-1451