We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Tumor microenvironment in thyroid cancer: Immune cells, patterns, and novel treatments.
- Authors
Febrero, Beatriz; Ruiz‐Manzanera, Juan José; Ros‐Madrid, Inmaculada; Hernández, Antonio Miguel; Orenes‐Piñero, Esteban; Rodríguez, José Manuel
- Abstract
The tumor immune microenvironment of thyroid cancer is the heterogeneous histological space in which tumor cells coexist with host cells. Published data from this review were identified by search and selection database of Pubmed, Elsevier, and Science Direct. Searching was made in two steps using different keywords. In thyroid pathology, the inflammatory response is very important, and might have a key role finding new diagnostic and therapeutic methods, particularly in thyroid cancer. Different immune cells may be more or less present in different types of thyroid cancer and may even have different functions, hence the importance of knowing their presence in different thyroid tumor pathologies. Cancer‐related inflammation could be a useful target for new diagnostic and therapeutic strategies by analyzing peritumoral and intratumoral immune cells in different types of thyroid tumors. Moreover, novel strategies for thyroid cancer treatments, such as monoclonal antibodies targeting checkpoint inhibitors, are emerging as promising alternatives.
- Subjects
THYROID cancer; TUMOR microenvironment; THYROID gland tumors; CANCER cells; ANAPLASTIC thyroid cancer; MEDULLARY thyroid carcinoma
- Publication
Head & Neck, 2024, Vol 46, Issue 6, p1486
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.27695