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- Title
Radiation dose distribution in the teeth, maxilla, and mandible of patients with oropharyngeal and nasopharyngeal tumors who were treated with intensity-modulated radiotherapy.
- Authors
Parahyba, Cláudia Joffily; Ynoe Moraes, Fábio; Ramos, Pedro Augusto Minorim; Haddad, Cecília Maria Kalil; da Silva, João Luis Fernandes; Fregnani, Eduardo Rodrigues
- Abstract
Background The purpose of this study was to evaluate the distribution of the intensity-modulated radiotherapy (IMRT) dose delivered to the teeth, maxilla, and mandible. Methods The mean dose (Dmean) and maximum dose (Dmax) of radiation for the maxilla, mandible, and teeth of 63 patients with oropharyngeal ( n = 44) or nasopharyngeal ( n = 19) tumors were retrospectively evaluated. Results The posterior regions of the mandible received the highest doses, and the teeth received lower doses than the bones (maximum dose, p < .001; average dose, p < .001). The Dmax ( p < .001) and Dmean ( p < .001) depended on primary tumor location. The superior bones and teeth of patients with nasopharyngeal tumors received more radiation than those of patients with oropharyngeal tumors. Conclusion A dose distribution map was generated based on the estimated doses received, which could allow prediction of the areas most affected by radiation and facilitate further correlations with dental complications after radiotherapy. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1708-1716, 2016
- Subjects
ORAL diseases; DRUG dosage; RADIATION; TUMORS; DENTAL care
- Publication
Head & Neck, 2016, Vol 38, Issue 11, p1621
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.24479