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SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.
- Published in:
- EMBO Molecular Medicine, 2021, v. 13, n. 2, p. 1, doi. 10.15252/emmm.202012640
- By:
- Publication type:
- Article
Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.
- Published in:
- EMBO Journal, 2001, v. 20, n. 13, p. 3402, doi. 10.1093/emboj/20.13.3402
- By:
- Publication type:
- Article
Perspectives on the role of Wnt biology in cancer.
- Published in:
- Science Signaling, 2019, v. 12, n. 589, p. 1, doi. 10.1126/scisignal.aay4494
- By:
- Publication type:
- Article
Genetically engineered mouse models to evaluate the role of Wnt secretion in bone development and homeostasis.
- Published in:
- American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 2016, v. 172C, n. 1, p. 24, doi. 10.1002/ajmg.c.31474
- By:
- Publication type:
- Article
Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations.
- Published in:
- American Journal of Medical Genetics. Part A, 2015, v. 167A, n. 7, p. 1429, doi. 10.1002/ajmg.a.37048
- By:
- Publication type:
- Article
Insights Into the Mechanisms of Sclerostin Action in Regulating Bone Mass Accrual.
- Published in:
- Journal of Bone & Mineral Research, 2014, v. 29, n. 1, p. 24, doi. 10.1002/jbmr.2154
- By:
- Publication type:
- Article
Integration of cellular adhesion and Wnt signaling: Interactions between N-cadherin and LRP5 and their role in regulating bone mass.
- Published in:
- Journal of Bone & Mineral Research, 2012, v. 27, n. 9, p. 1849, doi. 10.1002/jbmr.1715
- By:
- Publication type:
- Article
Perspective: Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone.
- Published in:
- Journal of Bone & Mineral Research, 2009, v. 24, n. 2, p. 171, doi. 10.1359/jbmr.081235
- By:
- Publication type:
- Article
Decreased BMD and Limb Deformities in Mice Carrying Mutations in Both Lrp5 and Lrp6.
- Published in:
- Journal of Bone & Mineral Research, 2004, v. 19, n. 12, p. 2033, doi. 10.1359/jbmr.040907
- By:
- Publication type:
- Article
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
- Published in:
- Nature Medicine, 2014, v. 20, n. 11, p. 1229, doi. 10.1038/nm.3697
- By:
- Publication type:
- Article
Frizzled‐4 is required for normal bone acquisition despite compensation by Frizzled‐8.
- Published in:
- Journal of Cellular Physiology, 2020, v. 235, n. 10, p. 6673, doi. 10.1002/jcp.29563
- By:
- Publication type:
- Article
P53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.
- Published in:
- Nature, 1994, v. 371, n. 6492, p. 72, doi. 10.1038/371072a0
- By:
- Publication type:
- Article
Inhibiting WNT secretion reduces high bone mass caused by Sost loss-of-function or gain-of-function mutations in Lrp5.
- Published in:
- Bone Research, 2023, v. 11, n. 1, p. 1, doi. 10.1038/s41413-023-00278-5
- By:
- Publication type:
- Article
WNT signaling in bone development and homeostasis.
- Published in:
- WIREs: Developmental Biology, 2014, v. 3, n. 6, p. 489, doi. 10.1002/wdev.159
- By:
- Publication type:
- Article
Down Regulation of Wnt Signaling Mitigates Hypoxia-Induced Chemoresistance in Human Osteosarcoma Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0111431
- By:
- Publication type:
- Article
Characterization of the Molecular Mechanism of the Bone-Anabolic Activity of Carfilzomib in Multiple Myeloma.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074191
- By:
- Publication type:
- Article
Targeting the Giant Cell Tumor Stromal Cell: Functional Characterization and a Novel Therapeutic Strategy.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069101
- By:
- Publication type:
- Article
Mice Lacking Pten in Osteoblasts Have Improved Intramembranous and Late Endochondral Fracture Healing
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063857
- By:
- Publication type:
- Article
Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063323
- By:
- Publication type:
- Article
An Accurate Prostate Cancer Prognosticator Using a Seven-Gene Signature Plus Gleason Score and Taking Cell Type Heterogeneity into Account.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045178
- By:
- Publication type:
- Article
Modulation of β-Catenin Signaling by Glucagon Receptor Activation.
- Published in:
- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033676
- By:
- Publication type:
- Article
The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage.
- Published in:
- PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006594
- By:
- Publication type:
- Article
The Wnt Co-Receptor Lrp6 Is Required for Normal Mouse Mammary Gland Development.
- Published in:
- PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005813
- By:
- Publication type:
- Article
Deficiency of FLCN in Mouse Kidney Led to Development of Polycystic Kidneys and Renal Neoplasia.
- Published in:
- PLoS ONE, 2008, v. 3, n. 10, p. 1, doi. 10.1371/journal.pone.0003581
- By:
- Publication type:
- Article
Independent validation of experimental results requires timely and unrestricted access to animal models and reagents.
- Published in:
- PLoS Genetics, 2020, v. 16, n. 6, p. 1, doi. 10.1371/journal.pgen.1008940
- By:
- Publication type:
- Article
An osteocalcin-deficient mouse strain without endocrine abnormalities.
- Published in:
- PLoS Genetics, 2020, v. 16, n. 5, p. 1, doi. 10.1371/journal.pgen.1008361
- By:
- Publication type:
- Article
LDL receptor‐related protein LRP6 senses nutrient levels and regulates Hippo signaling.
- Published in:
- EMBO Reports, 2020, v. 21, n. 9, p. 1, doi. 10.15252/embr.202050103
- By:
- Publication type:
- Article
The Past, Present, and Future of Genetically Engineered Mouse Models for Skeletal Biology.
- Published in:
- Biomolecules (2218-273X), 2023, v. 13, n. 9, p. 1311, doi. 10.3390/biom13091311
- By:
- Publication type:
- Article
Wnt/ß-catenin Signaling in Normal and Cancer Stem Cells.
- Published in:
- Cancers, 2011, v. 3, n. 2, p. 2050, doi. 10.3390/cancers3022050
- By:
- Publication type:
- Article
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
- Published in:
- Nature, 2011, v. 474, n. 7352, p. 511, doi. 10.1038/nature10085
- By:
- Publication type:
- Article
A comparative evaluation of β-catenin and plakoglobin signaling activity.
- Published in:
- Oncogene, 2000, v. 19, n. 50, p. 5720, doi. 10.1038/sj.onc.1203921
- By:
- Publication type:
- Article
Development of a flexible and specific gene delivery system for production of murine tumor models.
- Published in:
- Oncogene, 1999, v. 18, n. 38, p. 5253, doi. 10.1038/sj.onc.1203087
- By:
- Publication type:
- Article
Mouse Models of Prostate Cancer.
- Published in:
- Prostate Cancer (20903111), 2011, p. 1, doi. 10.1155/2011/895238
- By:
- Publication type:
- Article
Accelerated and increased joint damage in young mice with global inactivation of mitogen-inducible gene 6 after ligament and meniscus injury.
- Published in:
- Arthritis Research & Therapy, 2014, v. 16, n. 1, p. R81, doi. 10.1186/ar4522
- By:
- Publication type:
- Article
LRP5 and LRP6 Are Not Required for Protective Antigen-Mediated Internalization or Lethality of Anthrax Lethal Toxin.
- Published in:
- PLoS Pathogens, 2007, v. 3, n. 3, p. 0287, doi. 10.1371/journal.ppat.0030027
- By:
- Publication type:
- Article
Lrp5 and Lrp6 play compensatory roles in mouse intestinal development.
- Published in:
- Journal of Cellular Biochemistry, 2012, v. 113, n. 1, p. 31, doi. 10.1002/jcb.23324
- By:
- Publication type:
- Article
Endometrial hyperplasia with loss of APC in a novel population of Lyz2-expressing mouse endometrial epithelial cells.
- Published in:
- Carcinogenesis, 2023, v. 44, n. 1, p. 54, doi. 10.1093/carcin/bgac101
- By:
- Publication type:
- Article
Concurrent Hepsin overexpression and adenomatous polyposis coli deletion causes invasive prostate carcinoma in mice.
- Published in:
- Prostate, 2015, v. 75, n. 14, p. 1579, doi. 10.1002/pros.23032
- By:
- Publication type:
- Article
Activation of Wnt/β-catenin signaling in a subpopulation of murine prostate luminal epithelial cells induces high grade prostate intraepithelial neoplasia.
- Published in:
- Prostate, 2014, v. 74, n. 15, p. 1506, doi. 10.1002/pros.22868
- By:
- Publication type:
- Article
Wntless spatially regulates bone development through β-catenin-dependent and independent mechanisms.
- Published in:
- Developmental Dynamics, 2015, v. 244, n. 10, p. 1347, doi. 10.1002/dvdy.24316
- By:
- Publication type:
- Article
Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 15, p. 2949, doi. 10.1093/hmg/ddx183
- By:
- Publication type:
- Article
The activation of β-catenin by Gαs contributes to the etiology of phenotypes seen in Fibrous dysplasia and McCune-Albright syndrome.
- Published in:
- IBMS BoneKEy, 2012, v. 9, n. 6, p. 113, doi. 10.1038/bonekey.2012.113
- By:
- Publication type:
- Article
Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02413-3
- By:
- Publication type:
- Article
Loss of Lgals3 Protects Against Gonadectomy-Induced Cortical Bone Loss in Mice.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Mutation of the galectin‐3 glycan‐binding domain (Lgals3‐R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice.
- Published in:
- FEBS Open Bio, 2022, v. 12, n. 10, p. 1717, doi. 10.1002/2211-5463.13483
- By:
- Publication type:
- Article
Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6
- Published in:
- FEBS Letters, 2008, v. 582, n. 2, p. 255, doi. 10.1016/j.febslet.2007.12.013
- By:
- Publication type:
- Article
Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways.
- Published in:
- 2019
- By:
- Publication type:
- Correction Notice
LRP1 Suppresses Bone Resorption in Mice by Inhibiting the RANKL‐Stimulated NF‐κB and p38 Pathways During Osteoclastogenesis.
- Published in:
- Journal of Bone & Mineral Research, 2018, v. 33, n. 10, p. 1773, doi. 10.1002/jbmr.3469
- By:
- Publication type:
- Article
CRISPR/CAS9 Technologies.
- Published in:
- 2017
- By:
- Publication type:
- Other