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- Title
Clinical Characteristics of Anhedonia in Japanese Patients with Parkinson's Disease.
- Authors
Harada, Toshihide; Ishizaki, Fumiko; Horie, Nobuko; Katsuoka, Hiroyuki; Nitta, Yumiko; Yamada, Tohru; Nitta, Kohsaku
- Abstract
Objective: It has been reported that mood disorder is often associated with Parkinson's disease. The mood disorder with Parkinson's disease is considered to be different from the symptoms with major depression and equal to anhedonia caused by the dysfunction of dopaminergic neural transmission circuit. Recently Snaith-Hamilton Pleasure Scale (SUM'S) has been rapidly widespread for the purpose of evaluating anhedonia in Europe and America. Design: A clinical study. Materials and Methods: We evaluated mood condition using the SHAPS and analyzed the appearance frequency of anhedonia in the parkinsonian patients in Japan. Results: The patients with Parkinson's disease often revealed diminished hedonic tone and hedonic anhedonia and the frequency was approximately 60%. The results "eve similar to those in Europe and America. Conclusions: It is necessary to advance the clarification of pathogenesis of anhedonia and the development of the treatment for anhedonia in the parkinsonian patients in Japan.
- Subjects
JAPAN; ANALYSIS of variance; ANHEDONIA; PARKINSON'S disease; QUALITY of life; CASE-control method; SYMPTOMS
- Publication
International Medical Journal, 2011, Vol 18, Issue 3, p185
- ISSN
1341-2051
- Publication type
Article