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- Title
In vivo Stimulus-Induced Vasodilation Occurs without IP<sub>3</sub> Receptor Activation and May Precede Astrocytic Calcium Increase.
- Authors
Nizar, Krystal; Uhlirova, Hana; Tian, Peifang; Saisan, Payam A.; Cheng, Qun; Reznichenko, Lidia; Weldy, Kimberly L.; Steed, Tyler C.; Sridhar, Vishnu B.; MacDonald, Christopher L.; Cui, Jianxia; Gratiy, Sergey L.; Sakadzic, Sava; Boas, David A.
- Abstract
The article discusses a research which analyzes the occurring of in-vivo stimulus-induced vasodilation without activation of inositol triphosphate (IP3) receptor activation and possibly precedes the increase of astrocytic calcium. Various methods for performing the research are described including two-photon imaging, stimulation and data analysis. Sporadic calcium increase due to astrocytes in robust neuronal response's presence is discussed in the results.
- Subjects
VASODILATION; CALCIUM in the body; INOSITOL trisphosphate receptors; IMAGING systems; NEURAL stimulation; DATA analysis
- Publication
Journal of Neuroscience, 2013, Vol 33, Issue 19, p8411
- ISSN
0270-6474
- Publication type
Article
- DOI
10.1523/JNEUROSCI.3285-12.2013