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- Title
Proton MR spectroscopy of the brain in patients treated with TIPS.
- Authors
Hamuro, M.; Nakamura, K.; Matsuoka, T.; Kaminou, T.; Higashida, M.; Yamada, R.
- Abstract
<bold>Purpose: </bold>To evaluate the utility of proton MR spectroscopy (MRS) for the early detection of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunting (TIPS).<bold>Material and Methods: </bold>Six patients, who underwent TIPS for treatment of portal hypertension, were examined by MRS I week before and 1 week after TIPS. They were simultaneously clinically examined for number connection test, blood NH3 level, liver function test and the Fischer ratio.<bold>Result: </bold>Three of 6 patients showed overt HE 1 to 5 weeks after TIPS and the other 3 patients did not show overt HE. The overt HE group showed the larger ratio of the amounts of glutamine and glutamate/myo-inositol (Glx/MI) than that of non-overt HE group (p<0.05).<bold>Conclusion: </bold>The Glx/MI ratio estimated by MRS was useful for early detection of HE after TIPS.
- Subjects
NEUROHYPOPHYSIS; GERM cell tumors; INFUNDIBULUM (Brain)
- Publication
Acta Radiologica, 2000, Vol 41, Issue 6, p567
- ISSN
0284-1851
- Publication type
journal article
- DOI
10.1080/028418500127345910