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- Title
Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice.
- Authors
Hull, Rebecca L.; Hull, R L; Verchere, C B; Andrikopoulos, S; Wang, F; Vidal, J; Kahn, S E
- Abstract
Examines the effect of oophorectomy on island of Langerhans cells in human islet amyloid polypeptide transgenic mice. Promotion of amyloid formation; Decrease in pancreatic beta-cell function; Association of high-fat diet with the enhancement of amyloid formation.
- Subjects
OVARIECTOMY; AMYLOID; PROTEIN metabolism; ANIMAL experimentation; COMPARATIVE studies; FAT content of food; ISLANDS of Langerhans; RESEARCH methodology; MEDICAL cooperation; MICE; PROTEINS; RESEARCH; SEX distribution; EVALUATION research; PANCREATIC hormones
- Publication
Diabetes, 2001, Vol 50, pS184
- ISSN
0012-1797
- Publication type
journal article
- DOI
10.2337/diabetes.50.2007.S184