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Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets.
- Published in:
- Diabetologia, 2009, v. 52, n. 4, p. 636, doi. 10.1007/s00125-009-1274-2
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- Publication type:
- Article
Comment on: Nathan DM, Buse JB, Davidson MB et al (2006) Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 49:1711–1721
- Published in:
- 2007
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- Publication type:
- Letter
K-value and low insulin secretion in a non-obese white population: predicted glucose tolerance after 25 years.
- Published in:
- Diabetologia, 2005, v. 48, n. 11, p. 2262, doi. 10.1007/s00125-005-1929-6
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- Publication type:
- Article
Mitochondrial regulation of insulin production in rat pancreatic islets.
- Published in:
- Diabetologia, 2005, v. 48, n. 8, p. 1549, doi. 10.1007/s00125-005-1811-6
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- Publication type:
- Article
Regulation of insulin gene transcription.
- Published in:
- Diabetologia, 2002, v. 45, n. 3, p. 309, doi. 10.1007/s00125-001-0728-y
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- Publication type:
- Article
Long in the shade, glucagon re-occupies centre court.
- Published in:
- Diabetes, Obesity & Metabolism, 2011, v. 13, p. v, doi. 10.1111/j.1463-1326.2011.01476.x
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- Publication type:
- Article
What ails the β-cell?
- Published in:
- Diabetes, Obesity & Metabolism, 2010, p. 1, doi. 10.1111/j.1463-1326.2010.01296.x
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- Publication type:
- Article
Balancing needs and means: the dilemma of the β-cell in the modern world.
- Published in:
- Diabetes, Obesity & Metabolism, 2009, v. 11, p. 1, doi. 10.1111/j.1463-1326.2009.01101.x
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- Publication type:
- Article
The role of mTOR in the adaptation and failure of β-cells in type 2 diabetes.
- Published in:
- Diabetes, Obesity & Metabolism, 2008, v. 10, p. 157, doi. 10.1111/j.1463-1326.2008.00952.x
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- Publication type:
- Article
Neuronal nitric oxide synthase protects the pancreatic beta cell from glucolipotoxicity-induced endoplasmic reticulum stress and apoptosis.
- Published in:
- Diabetologia, 2010, v. 53, n. 10, p. 2177, doi. 10.1007/s00125-010-1833-6
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- Publication type:
- Article
The Islet and Metabolism Keep Time.
- Published in:
- 2015
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- Publication type:
- Editorial
Donald F. Steiner: great scientist, close friend, real 'Mensch'.
- Published in:
- Diabetes, Obesity & Metabolism, 2015, v. 17, p. 1, doi. 10.1111/dom.12530
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- Publication type:
- Article
The mind and the belly: a glance at how the nervous system directs metabolism.
- Published in:
- Diabetes, Obesity & Metabolism, 2014, v. 16, p. 1, doi. 10.1111/dom.12353
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- Publication type:
- Article
Shifting the paradigm of islet inflammation-good guy or bad guy?
- Published in:
- Diabetes, Obesity & Metabolism, 2013, v. 15, p. 4, doi. 10.1111/dom.12184
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- Publication type:
- Article
Binding, internalization, and degradation of insulin in vascular endothelial cells.
- Published in:
- 1982
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- Publication type:
- journal article
Effect of diet-induced obesity on glucose and insulin tolerance of a rodent with a low insulin response (Acomys cahirinus).
- Published in:
- 1979
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- Publication type:
- journal article
Quantitative determination of the interaction between epinephrine and various insulin releasers in man.
- Published in:
- 1978
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- Publication type:
- journal article
Potentiation of glucose-induced insulin release by glucose in the isolated pancreas of fed and fasted rats.
- Published in:
- 1976
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- Publication type:
- journal article
Insulin secretion in the spiny mouse (Acomys cahirinus). Dose and time kinetic studies with glucose in vivo and in vitro.
- Published in:
- 1975
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- Publication type:
- journal article
Decreased cyclic AMP and insulin response to glucose in isolated islets of neonatal rats.
- Published in:
- 1975
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- Publication type:
- journal article
Quantitative study on the potentiating effect of arginine on glucose-induced insulin response in healthy, prediabetic, and diabetic subjects.
- Published in:
- 1974
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- Publication type:
- journal article
Glutamine and glutamate metabolism in normal and diabetic subjects.
- Published in:
- 1973
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- Publication type:
- journal article
Decreased sensitivity of the pancreatic beta cells to glucose in prediabetic and diabetic subjects. A glucose dose-response study.
- Published in:
- 1972
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- Publication type:
- journal article
"What is inherited--what is added" hypothesis for the pathogenesis of diabetes mellitus.
- Published in:
- 1967
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- Publication type:
- journal article
Trauma: Hormonal Factors with Special Reference to Diabetes Mellitus.
- Published in:
- Acta Anaesthesiologica Scandinavica, 1974, v. 18, p. 107, doi. 10.1111/j.1399-6576.1974.tb00713.x
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- Publication type:
- Article
Glycosylated serum protein levels assayed with highly sensitive immunoradiometric assay accurately reflect glycemic control of diabetic patients.
- Published in:
- 1992
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- Publication type:
- journal article
Toward a systems biology of insulin secretion and type 2 diabetes.
- Published in:
- 2006
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- Publication type:
- Journal Article
Dynamics of glucose-induced localization of PKC isoenzymes in pancreatic beta-cells: diabetes-related changes in the GK rat.
- Published in:
- 2006
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- Publication type:
- journal article
IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes.
- Published in:
- 2001
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- Publication type:
- journal article
Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes.
- Published in:
- 2001
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- Publication type:
- journal article
beta-cell-specific expression of insulin and PDX-1 genes.
- Published in:
- 2001
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- Publication type:
- journal article
beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes.
- Published in:
- 2001
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- Publication type:
- journal article
Regulatory elements involved in human pdx-1 gene expression.
- Published in:
- 2001
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- Publication type:
- journal article
The islet in type 2 diabetes: back to center stage.
- Published in:
- 2001
- By:
- Publication type:
- Editorial
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
- Published in:
- 2001
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- Publication type:
- journal article
Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose.
- Published in:
- 1999
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- Publication type:
- journal article
Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.
- Published in:
- 1999
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- Publication type:
- journal article
Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes.
- Published in:
- 1999
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- Publication type:
- journal article
Characterization of the unusual insulin of Psammomys obesus, a rodent with nutrition-induced NIDDM-like syndrome.
- Published in:
- 1997
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- Publication type:
- journal article
In vitro autoregulation of glucose utilization in rat soleus muscle.
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- 1987
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- Publication type:
- journal article
Somatostatin impairs clearance of exogenous insulin in humans.
- Published in:
- 1987
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- Publication type:
- journal article
Insulin deficiency and insulin resistance in Type 2 (non-insulin-dependent) diabetes: quantitative contributions of pancreatic and peripheral responses to glucose homeostasis.
- Published in:
- European Journal of Clinical Investigation, 1987, v. 17, n. 3, p. 266, doi. 10.1111/j.1365-2362.1987.tb01247.x
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- Publication type:
- Article
A Mathematical Model for the Glucose Induced Insulin Release in Man.
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- European Journal of Clinical Investigation, 1974, v. 4, n. 4, p. 267, doi. 10.1111/j.1365-2362.1974.tb02345.x
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- Publication type:
- Article
A Mathematical Model for the Glucose Induced Insulin Release in Man.
- Published in:
- European Journal of Clinical Investigation, 1974, v. 4, n. 1, p. 267, doi. 10.1111/j.1365-2362.1974.tb00403.x
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- Publication type:
- Article
The Regulation of Splanchnic Glucose Production in Subjects with Low Insulin Response - a Compensatory Mechanism in Prediabetes?
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- European Journal of Clinical Investigation, 1973, v. 3, n. 3, p. 193, doi. 10.1111/j.1365-2362.1973.tb00349.x
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- Publication type:
- Article
Genetic regulation of the kinetics of glucose-induced insulin release in man Studies in families with diabetic and non-diabetic probands.
- Published in:
- Clinical Genetics, 1985, v. 28, n. 1, p. 8, doi. 10.1111/j.1399-0004.1985.tb01210.x
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- Publication type:
- Article
Evidence for an autosomal recessive gene regulating the persistence of the insulin response to glucose in man.
- Published in:
- Clinical Genetics, 1982, v. 22, n. 4, p. 180, doi. 10.1111/j.1399-0004.1982.tb01432.x
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- Publication type:
- Article