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- Title
Phytochemical Screening and Toxicological Evaluation of Pyrrosia piloselloides Extracts.
- Authors
Arif, Muhammad Zaim; Zainuddin, Nik Aina Syazana Nik; Zakaria, Intan Suziana; Wahab, Wan Nor Amilah Wan Abdul; Sul'ain, Mohd Dasuki
- Abstract
Objective: Pyrrosia piloselloides (PP) is a type of fern that grows wildly in South East Asia which has been used as traditional medicine for aborginal people to cure various health problems such as cough and dysentery. The present work aimed to detect the presence of potential bioactive compound and toxic substances in ethanol and aqueous PP extracts as well as to determine the toxicity of the ethanol and aqueous PP extract. Design: The ethanol and aqueous PP extracts were screened for their phytochemical constituents and toxicity. Materials and Methods: Phytochemical screening was conducted using standard method, while toxicity tests were conducted using brine shrimp lethality test (BLST) and atomic absorption spectroscopy (AAS) for heavy metal analysis in order to detect the presence of zinc (Zn), copper (Cu), lead (Pb), cadmium (Cd), chromium (Cr) and manganese (Mn). Results: Both ethanol and aqueous extracts showed the presence of potential bioactive compounds such as phenols, flavonoids, tannins, terpenoids, saponins and sterol. Lethal concentrations (LC50) for BSLT in both extracts were more than 1000 ppm. The level of heavy metals in this plant was within acceptable range for Zn, Cu and Mn while Pb, Cd and Cr were not detected. Conclusion: In conclusion, the presence of phytochemicals in PP extracts justified its potential to be used as a source of alternative medicine and also considered safe for consumption.
- Subjects
COPPER analysis; CHROMIUM analysis; CADMIUM analysis; LEAD analysis; ZINC analysis; ALTERNATIVE medicine; BIOLOGICAL assay; DRUG design; CLINICAL drug trials; ETHANOL; FLAVONOIDS; MANGANESE; PHENOLS; PLANTS; SPECTRUM analysis; STEROLS; TANNINS; TERPENES; TOXICITY testing; TRADITIONAL medicine; PHYTOCHEMICALS; PLANT extracts
- Publication
International Medical Journal, 2018, Vol 25, Issue 3, p177
- ISSN
1341-2051
- Publication type
Article