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- Title
HISTOPLASMIN SURVEY IN HIV-POSITIVE PATIENTS: RESULTS FROM AN ENDEMIC AREA IN NORTHEASTERN BRAZIL.
- Authors
BEZERRA, Fabricia Salvador; ZANCOPÉ-OLIVEIRA, Rosely Maria; Nogueira BRILHANTE, Raimunda Samia; WANKE, Bodo; MOTA, Rosa Maria Salani; RAMOS, Ana Paula Gomes; RAMOS Jr., Alberto Novaes; FAÇANHA, Mônica Cardoso; Jesus Silva LEITÃO, Terezinha do Menino
- Abstract
Background. Disseminated histoplasmosis is common in AIDS patients with advanced immunosuppression in Ceará, Northeastern Brazil. The goal of this study was to determine the prevalence ofHistoplasma infection in patients with HIV/AIDS living in Fortaleza, the capital of Ceará. Methods. Intradermal tests with histoplasmin (mycelial phase) were performed in 161 HIV patients with CD4 ≥ 350 cells/mm³. Evidence of recent illness was evaluated with immunodiffusion (ID) tests in 76 of these individuals. Results. A total of 11.8% of patients reacted to histoplasmin and 2.63% had ID test positive to Histoplasma. The presence of mango trees (Mangifera indica) in the patient neighborhood (OR = 2.870; 95% CI = 1.081-7.617; p = 0.040) and past activity involving soil (OR = 2.834; 95% CI= 1.045-7.687; p = 0.045) or visits to afarm (OR = 3.869; 95% CI = 1.189-12.591; p = 0.033) were significantly associated with Histoplasma infection. Conclusions. Patients with HIV living in Fortaleza have an expressive prevalence of infection with Histoplasma.
- Subjects
HISTOPLASMOSIS; IMMUNOSUPPRESSION; HIV-positive persons; HIV infections; INFECTION; MANGIFERA
- Publication
Revista do Instituto de Medicina Tropical de São Paulo, 2013, Vol 55, Issue 4, p261
- ISSN
0036-4665
- Publication type
Article
- DOI
10.1590/S0036-46652013000400007